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Re: Heredity B/Designer Genes C

Posted: February 4th, 2020, 10:19 am
by Tailsfan101
Here wrote: February 4th, 2020, 10:16 am revival!
1. What does RFLP stand for and what is it primarily used for?
2. Who developed DNA fingerprinting?
3. What is the prokaryotic promoter at the -35 element?
1. Restriction Fragment Length Polymorphisms, they are used as genetic markers for DNA cutting
2. Alec Jeffreys
3. TTGACA

Re: Heredity B/Designer Genes C

Posted: February 4th, 2020, 10:23 am
by Here
Tailsfan101 wrote: February 4th, 2020, 10:19 am
Here wrote: February 4th, 2020, 10:16 am revival!
1. What does RFLP stand for and what is it primarily used for?
2. Who developed DNA fingerprinting?
3. What is the prokaryotic promoter at the -35 element?
1. Restriction Fragment Length Polymorphisms, they are used as genetic markers for DNA cutting
2. Alec Jeffreys
3. TTGACA
all good! your turn

Re: Heredity B/Designer Genes C

Posted: February 4th, 2020, 12:52 pm
by Tailsfan101
A template DNA strand (top) and a coding DNA strand (bottom) are shown below:

3' TACCATATACCGACT 5'
5' ATGGTATATGGCTGA 3'

Label the following point mutations:

1.

3' TACCCATATACCGACT 5'
5' ATGGGTATATGGCTGA 3'

2.

3' TACCATATACCGCCT 5'
5' ATGGTATATGGCGGA 3'

3.

3' TACCATAGACCGACT 5'
5' ATGGTATCTGGCTGA 3'

Re: Heredity B/Designer Genes C

Posted: February 6th, 2020, 5:31 pm
by Phenakism
Tailsfan101 wrote: February 4th, 2020, 12:52 pm A template DNA strand (top) and a coding DNA strand (bottom) are shown below:

3' TACCATATACCGACT 5'
5' ATG GTA TAT GGC TGA 3'

Label the following point mutations:

1.

3' TACCCATATACCGACT 5'
5' ATG GGT ATA TGG CTG A 3'

2.

3' TACCATATACCGCCT 5'
5' ATG GTA TAT GGC GGA 3'

3.

3' TACCATAGACCGACT 5'
5' ATG GTA TCT GGC TGA 3'
1. conservative missense 
2. a stop codon mutation? idk what its called maybe antimissense
3. non conservative missense 
I thinks that's what you meant?

Re: Heredity B/Designer Genes C

Posted: February 7th, 2020, 9:45 am
by Tailsfan101
Phenakism wrote: February 6th, 2020, 5:31 pm
Tailsfan101 wrote: February 4th, 2020, 12:52 pm A template DNA strand (top) and a coding DNA strand (bottom) are shown below:

3' TACCATATACCGACT 5'
5' ATG GTA TAT GGC TGA 3'

Label the following point mutations:

1.

3' TACCCATATACCGACT 5'
5' ATG GGT ATA TGG CTG A 3'

2.

3' TACCATATACCGCCT 5'
5' ATG GTA TAT GGC GGA 3'

3.

3' TACCATAGACCGACT 5'
5' ATG GTA TCT GGC TGA 3'
1. conservative missense 
2. a stop codon mutation? idk what its called maybe antimissense
3. non conservative missense 
I thinks that's what you meant?
For #1, I was looking for frameshift. The other two look good, your turn!

Re: Heredity B/Designer Genes C

Posted: February 12th, 2020, 5:29 pm
by Phenakism
A newly found isolated population in South America which theoretically is in Hardy-Weinberg equilibrium has been discovered. A scientist takes a survey of the 3562 pop. group to find that the group suffers from malaria. The population also suffers from sickle cell anemia, as the recessive allele for sickle cell has a frequency of 46% in the population (sickle cell is a autosomal recessive disease).

1. How much (%) of the population actually has sickle cell anemia?

2. How many people have resistance to malaria?

3. How many people are immune to malaria and are free from sickle cell anemia?

Re: Heredity B/Designer Genes C

Posted: February 14th, 2020, 4:05 pm
by Tailsfan101
Phenakism wrote: February 12th, 2020, 5:29 pm A newly found isolated population in South America which theoretically is in Hardy-Weinberg equilibrium has been discovered. A scientist takes a survey of the 3562 pop. group to find that the group suffers from malaria. The population also suffers from sickle cell anemia, as the recessive allele for sickle cell has a frequency of 46% in the population (sickle cell is a autosomal recessive disease).

1. How much (%) of the population actually has sickle cell anemia?

2. How many people have resistance to malaria?

3. How many people are immune to malaria and are free from sickle cell anemia?
1. 21.16%
2. 70.84%
3. 49.68%

Re: Heredity B/Designer Genes C

Posted: February 14th, 2020, 7:12 pm
by Phenakism
Tailsfan101 wrote: February 14th, 2020, 4:05 pm
Phenakism wrote: February 12th, 2020, 5:29 pm A newly found isolated population in South America which theoretically is in Hardy-Weinberg equilibrium has been discovered. A scientist takes a survey of the 3562 pop. group to find that the group suffers from malaria. The population also suffers from sickle cell anemia, as the recessive allele for sickle cell has a frequency of 46% in the population (sickle cell is a autosomal recessive disease).

1. How much (%) of the population actually has sickle cell anemia?

2. How many people have resistance to malaria?

3. How many people are immune to malaria and are free from sickle cell anemia?
1. 21.16%
2. 70.84%
3. 49.68%
All correct, though for 2 and 3 I was looking for a number of people not a percent, sorry bout that. Your turn!

Re: Heredity B/Designer Genes C

Posted: February 15th, 2020, 2:18 pm
by Tailsfan101
List the three steps in post-transcriptional modification, and, if applicable, which end of the mRNA is altered by them.

Re: Heredity B/Designer Genes C

Posted: February 15th, 2020, 3:18 pm
by Phenakism
Tailsfan101 wrote: February 15th, 2020, 2:18 pm List the three steps in post-transcriptional modification, and, if applicable, which end of the mRNA is altered by them.
1. Splicing of all the introns 2. Polyadenylation on the 3' end 3. Adding of the 5' cap