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Re: Protein Modeling C

Posted: September 9th, 2018, 12:20 pm
by nicholasmaurer
freed2003 wrote:
nicholasmaurer wrote:
freed2003 wrote:Does anyone know if we still have to study general protein knowledge for the test? On the rules it just states the test will have questions specific to the onsite protein, CRISPR, and protein folding.
3.III.b.i does not limit itself to CRISPR Cas9
But it does limit itself to protein folding(specifically the process that drive it) where past test contained more general protein questions(such as "what amino acid contains sulfur?")
True. I do expect fewer general knowledge questions than in past iterations of this event. However, it is hard to discuss the chemistry of protein folding with knowing that methionine contains sulfur and is responsible for disulfide bonds. There are lots of indirect areas of proteins that are required to address protein folding. But this should still be much narrower than the previous rules allowed, where tests often became collections of random trivia.

Re: Protein Modeling C

Posted: September 9th, 2018, 5:27 pm
by luanne
So all the extra knowledge we are suppose to know is going to be posted on the MSOE website? or is there an outside source that is also useful?

Re: Protein Modeling C

Posted: September 9th, 2018, 5:47 pm
by luanne
but to get this straight: to get what we are suppose to be modeling for the prebuild, in Jmol the command should be restrict 1-85 then restrict :b
correct?

Re: Protein Modeling C

Posted: September 9th, 2018, 7:32 pm
by CookiePie1
luanne wrote:but to get this straight: to get what we are suppose to be modeling for the prebuild, in Jmol the command should be restrict 1-85 then restrict :b
correct?
worked for me

Re: Protein Modeling C

Posted: September 10th, 2018, 10:51 am
by luanne
platypusomelette wrote:I've been doing "display 1-85 and not dna" but I still end up with one DNA strand. Has anyone been able to isolate it yet?
late response but if u do "restrict :b" and "restrict 1-85" it should just give you the backbone

Re: Protein Modeling C

Posted: September 17th, 2018, 6:10 pm
by saioly
on the rules, it is said that we need to be able to answer questions based on the on-site build as well. based on how protein modeling went in 2015 there was a learning module on cbm.msoe.edu. that site hasn't been updated with this year's model yet, so does anyone know when it will be updated?

thanks

Re: Protein Modeling C

Posted: September 17th, 2018, 6:27 pm
by luanne
saioly wrote:on the rules, it is said that we need to be able to answer questions based on the on-site build as well. based on how protein modeling went in 2015 there was a learning module on cbm.msoe.edu. that site hasn't been updated with this year's model yet, so does anyone know when it will be updated?

thanks
well, we just typically wait and see lol
but i expect it to be up by next month, becuase invitationals start soon
But if you want to get a head start on general knowledge there is the past event page.. just ignore the material that is protein-specific.
http://cbm.msoe.edu/scienceOlympiad/mod ... /index.php

Re: Protein Modeling C

Posted: September 19th, 2018, 4:10 pm
by daydreamer0023
luanne wrote:
saioly wrote:on the rules, it is said that we need to be able to answer questions based on the on-site build as well. based on how protein modeling went in 2015 there was a learning module on cbm.msoe.edu. that site hasn't been updated with this year's model yet, so does anyone know when it will be updated?

thanks
well, we just typically wait and see lol
but i expect it to be up by next month, becuase invitationals start soon
But if you want to get a head start on general knowledge there is the past event page.. just ignore the material that is protein-specific.
http://cbm.msoe.edu/scienceOlympiad/mod ... /index.php
Rules clarification was posted today. Apparently we're building the Anti-CRISPR protein instead...

Re: Protein Modeling C

Posted: September 19th, 2018, 5:38 pm
by Unome

Re: Protein Modeling C

Posted: September 20th, 2018, 7:16 am
by daydreamer0023
nicholasmaurer wrote:
freed2003 wrote:
nicholasmaurer wrote:
3.III.b.i does not limit itself to CRISPR Cas9
But it does limit itself to protein folding(specifically the process that drive it) where past test contained more general protein questions(such as "what amino acid contains sulfur?")
True. I do expect fewer general knowledge questions than in past iterations of this event. However, it is hard to discuss the chemistry of protein folding with knowing that methionine contains sulfur and is responsible for disulfide bonds. There are lots of indirect areas of proteins that are required to address protein folding. But this should still be much narrower than the previous rules allowed, where tests often became collections of random trivia.
Correct me if I'm wrong, but I don't think that methionine can have disulfide bonds - are you referring to cysteine?