Protein Modeling C

[CookiePie1]

I'm attempting to learn as much as I can about CRISPR, but I feel lost because I either find sources that are way too in-depth and I cannot read them, or I find the most basic resources. Does anyone have any sources that are between the two, and I hate to say it but the fact that the rules only tell us to learn about CRISPR/Cas9 means I have no real idea what I should focus on and I'm stuck feeling like I'm either missing vital information or I'm going way to obscure. I have been to scioly.com and am currently going through their video series, but is that enough?

https://media.hhmi.org/biointeractive/click/CRISPR/ this website is pretty good for a basic understanding of the mechanism behind it. The videos on the CBM website are pretty good for a start as well. However, if you want to start going more in-depth about the topic you kinda have to start reading the research papers about it. I also reccomend going on the CBM website and finding last year's papers, which are also pretty good.

[rish-leti]

Does anyone have any tips on what to study for the jmol portion once past the basics? I'm fairly solid on biochemistry and manipulating jmol, but I dont really know what to study next because it seems like every single test throws something a little bit different at us. Should I be studying different types of proteins, or delving deeply into CRISPR/CAS9? Thank you!

[CookiePie1]

Does anyone have any tips on what to study for the jmol portion once past the basics? I'm fairly solid on biochemistry and manipulating jmol, but I dont really know what to study next because it seems like every single test throws something a little bit different at us. Should I be studying different types of proteins, or delving deeply into CRISPR/CAS9? Thank you!

At SOUP, the test writer kinda threw curveballs at us by asking us to identify random proteins. That's easy enough, given jmol, but then we were asked a bunch of questions about its function and random info about said proteins. So, maybe it is a good idea to study some stuff about different commonly studied proteins. The PDB MOTM is a good place to start for that. Also, delving deeply into crispr/cas9 is always a good idea given the topic for this year.

Maybe the soup test was a bit of an anomaly though.

[Jashan12]

What is a score to get you to place going to be like on like with everything overall. (Ex 70% on model, 99% on onsite, and 1% on test)?

[CookiePie1]

What is a score to get you to place going to be like on like with everything overall. (Ex 70% on model, 99% on onsite, and 1% on test)?

Depends on the competion, since every test is different and every tournament has different teams.

[NationalsAim]

Anyone have any tips for identifying good sidechains to include in the Pre-Build Model?

[CookiePie1]

Anyone have any tips for identifying good sidechains to include in the Pre-Build Model?

you should read the papers on the cbm website. A lot is detailed in there.

[MoMoney$$$;)0)]

Come on people we need to add to the best of 2020

Best of 2020

If you guys don't know how to add to the WIki, share me the photo privately, and I can add it on.

[tjmontgomery]

Hi. Does anyone have any information on if the pre-built for the 2021 competition is the same as last year or is it different? I know Protein Modeling is supposed to have a rule change but I am not sure what that will entail. Thanks

[tjmontgomery]

Hi. Does anyone have any information on if the pre-built for the 2021 competition is the same as last year or is it different? I know Protein Modeling is supposed to have a rule change but I am not sure what that will entail. Thanks

I think they meant that they would change the topic and therefore change the prebuild. This is just speculative though. Nobody really knows what's going on right now lol.