The ASP148/ARG233 salt bridge helps to lock XIAP against the binding cavity of caspase-3. It also helps maintain the shape of XIAP itself, of course, but by having an ionic bond between two residues that extend into the binding cleft from opposite sides, the binding position of XIAP in that cavity is stabilized.TheWiseGirl wrote:Thank you!EASTstroudsburg13 wrote:The numbers refer to the mass of each monomer is kilodaltons (kDa). You are correct in that they're a way to differentiate the monomers.Also, thanks for sharing pictures of your prebuild!
And now for another question, this one having to do with XIAP. Does anyone know what Arginine 233 does? I read something where Asp.148 of XIAP bonds to Arginine 233; does this just keep the structure of the protein?
Protein Modeling C
- Phenylethylamine
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Re: Protein Modeling C
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Re: Protein Modeling C
That makes sense; Thanks Phenyl!!Phenylethylamine wrote: The ASP148/ARG233 salt bridge helps to lock XIAP against the binding cavity of caspase-3. It also helps maintain the shape of XIAP itself, of course, but by having an ionic bond between two residues that extend into the binding cleft from opposite sides, the binding position of XIAP in that cavity is stabilized.
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Yes, just make sure you label it on your notecard.kalithepianist wrote:Urgent! We lost one of our blue end caps >< are we allowed to paint it?
And I have a few extras if you want it! Just send me a PM if you do... I'm staying in the dorms.
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Re: Protein Modeling C
So I ended up only getting 7th in my competition =(
I was going to ask if anyone knew what protein would be next year's model, then I read the replies and it's going to be replaced? Sad day )=
But- Good news is it'll be replaced by food science/genes!!! And that's what I'm most interested in. I want to be a Biochemist/agronomic genomist, and this looks like the same field! I will certainly prepare early next year- I want to place!
I was going to ask if anyone knew what protein would be next year's model, then I read the replies and it's going to be replaced? Sad day )=
But- Good news is it'll be replaced by food science/genes!!! And that's what I'm most interested in. I want to be a Biochemist/agronomic genomist, and this looks like the same field! I will certainly prepare early next year- I want to place!
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Re: Protein Modeling C
It's going to be replaced by Food Science (or possibly Materials Science). Heredity/Genes is replacing Microbe Mission. For me, neither of these really strikes me like Protein did, though Food Science seems intriguing.
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Re: Protein Modeling C
It's pretty much nitpicking to say which event is replacing which other event... Microbe and Protein are, together, being replaced by Designer Genes and Food Science, both of which sound like fantastic events that I'd love to do (I did Food Sci back in B Division, but looking at this year's B Div rules, it looks like they've changed it a lot, and for the better).EASTstroudsburg13 wrote:It's going to be replaced by Food Science (or possibly Materials Science). Heredity/Genes is replacing Microbe Mission. For me, neither of these really strikes me like Protein did, though Food Science seems intriguing.
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Re: Protein Modeling C
Technically Proteins fits under the "Chemistry" category of events while Microbes fits under the "Life Science" category... but again, that's just nitpicking.Phenylethylamine wrote:It's pretty much nitpicking to say which event is replacing which other event... Microbe and Protein are, together, being replaced by Designer Genes and Food Science, both of which sound like fantastic events that I'd love to do (I did Food Sci back in B Division, but looking at this year's B Div rules, it looks like they've changed it a lot, and for the better).EASTstroudsburg13 wrote:It's going to be replaced by Food Science (or possibly Materials Science). Heredity/Genes is replacing Microbe Mission. For me, neither of these really strikes me like Protein did, though Food Science seems intriguing.
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2013: Astro (2, 6) / Chem (2, 5) / Circuits (8, 36) / Diseases (1,1) / Fermi (N/A, 24) / Materials (1, N/A)
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2011: Astro(2,11) / Diseases (1,27) / Optics (1,13) / Proteins (2,15)
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2012 : Astro (1, 11) / Chem (N/A, 13) / Diseases (3, 1) / Optics (2, 3) / Sounds (2, 1)
2011: Astro(2,11) / Diseases (1,27) / Optics (1,13) / Proteins (2,15)
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Re: Protein Modeling C
I was referring to Designer Genes as Protein's successor because, come on, look at the subject material: what's more apropos to proteins than genetics? Also, the Protein supervisor referred to it that wayInfinity Flat wrote:Technically Proteins fits under the "Chemistry" category of events while Microbes fits under the "Life Science" category... but again, that's just nitpicking.Phenylethylamine wrote:It's pretty much nitpicking to say which event is replacing which other event... Microbe and Protein are, together, being replaced by Designer Genes and Food Science, both of which sound like fantastic events that I'd love to do (I did Food Sci back in B Division, but looking at this year's B Div rules, it looks like they've changed it a lot, and for the better).EASTstroudsburg13 wrote:It's going to be replaced by Food Science (or possibly Materials Science). Heredity/Genes is replacing Microbe Mission. For me, neither of these really strikes me like Protein did, though Food Science seems intriguing.
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Re: Protein Modeling C
True. I always though of Food Science replacing Protein since they're both more hands-on. Nobody's referring to MagLev replacing Protein, though. 
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